Terpenes 101: Caryophyllene
Posted by Tweedle Farms on Jan 21st 2026

When people talk about products like CBD flower, cannabinoids tend to dominate the conversation. Compounds like THC and CBD often get the spotlight, but they are only part of a much larger picture. Terpenes, the aromatic compounds found throughout the plant world, play an equally important role in shaping how cannabis looks, smells, tastes, and interacts with the body.
Unbeknownst to many, terpenes are found in countless plants beyond cannabis. They are responsible for the citrus aroma of lemons, the sharp bite of pine needles, the floral notes of lavender, and the warm spice of black pepper. In cannabis, terpenes help define each cultivar’s unique character while also contributing to its overall effects.
What Are Terpenes?
Terpenes are naturally occurring compounds produced by plants as part of their defense and communication systems. They help attract pollinators, deter pests, and protect plants from environmental stress. In cannabis, terpenes work alongside cannabinoids and other plant compounds to create a more complete and expressive experience.
Beyond aroma and flavor, many terpenes interact with receptors and pathways in the human body. This is one reason full-spectrum cannabis products are often valued for their complexity and balance.
Introducing β-Caryophyllene
One terpene in particular stands out for its unique behavior in the body: β-caryophyllene. Classified as a sesquiterpene, β-caryophyllene is widely found in nature. You will encounter it in black pepper, cloves, hops, rosemary, and cannabis, where it contributes a spicy, woody, and slightly peppery aroma.
What makes β-caryophyllene remarkable is that it does more than influence scent and flavor. Research has shown that it directly activates the CB2 receptor, one of the body’s primary cannabinoid receptors. CB2 receptors are primarily associated with immune function and inflammatory response, rather than psychoactive effects.
In addition to interacting with the endocannabinoid system, β-caryophyllene has also been shown to activate the TRPV1 ion channel. This pathway plays a role in sensing heat, regulating body temperature, and processing sensations like burning or pain. It is the same channel activated by compounds such as capsaicin, the molecule responsible for the heat in chili peppers.
Why β-Caryophyllene Is Called a Dietary Cannabinoid
β-caryophyllene occupies a rare and interesting category. It is naturally present in many foods and essential oils, it has been approved by the FDA as a food additive, and it interacts directly with cannabinoid receptors in the body.
Because of this unique combination, researchers refer to β-caryophyllene as a dietary cannabinoid. It is not exclusive to cannabis, yet it behaves like a cannabinoid by engaging the endocannabinoid system in a meaningful way.
This distinction makes β-caryophyllene especially compelling for those interested in plant-based wellness and the broader relationship between diet, botanicals, and the body.
Finding β-Caryophyllene at Tweedle Farms
At Tweedle Farms, β-caryophyllene appears across a wide range of our products. It is one of the most common terpenes found in cannabis and frequently shows up in cultivars known for warm, grounding, and spice-forward profiles.
To help you shop with intention, we regularly highlight products that are especially rich in a featured terpene. And if you are looking for something specific, like a myrcene-rich pre roll, or CBD wax high in pinene, our online store includes a terpene selector that allows you to filter products by terpene profile. Whether you are seeking β-caryophyllene or exploring other terpenes, this tool makes it easier to find products aligned with your preferences.
Keep Exploring
Terpenes are a powerful reminder that cannabis is more than just cannabinoids. Compounds like β-caryophyllene show how deeply plant chemistry can interact with the human body in unexpected ways. As research continues to evolve, understanding terpenes helps paint a clearer picture of why full-spectrum cannabis can be such a rich and nuanced experience.
If you are curious to learn more, explore our terpene-focused resources and discover how these aromatic compounds show up across the Tweedle Farms lineup.